2/18/2023 0 Comments Stryker spy agent green![]() ![]() ICG is detectable within 1 min of injection 5, and imaging can be performed in real time, making FA suitable for intraoperative enhanced reality of perfusion. ![]() After intravenous injection, ICG distributes through the vascular system bound to plasma proteins, and its immediate fluorescence detection correlates with areas of perfused tissue. ICG is approved for FA by the US Food and Drug Administration and European Medicines Agency, and is safe to use as side‐effects occur rarely 6. ICG is a cyanine dye with an absorption and emission peak in the near‐infrared region 6, at about 800 nm. FA is a technique that uses an imaging system capable of excitation and detection of the fluorescent contrast agent indocyanine green (ICG) 7. To aid the surgeon with assessment of gastrointestinal perfusion and determination of the optimal site for anastomosis, fluorescence angiography (FA) has gained support among gastrointestinal surgeons 5, 6. Adequate blood perfusion has been described as one of the key factors for adequate healing of the anastomosis, and is a surgically modifiable factor. Various risk factors have been associated with AL 3, 4. Leakage rates of up to 20 per cent are reported after restorative cancer resection of both the upper and lower gastrointestinal tract 1, 2. Anastomotic leakage (AL) remains one of the most severe complications after gastrointestinal cancer surgery with restoration of continuity. ![]()
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